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Saitou Eijirou is a newly established intern doctor, who is forced to take on a second night job at another, much smaller hospital because of the extremely low pay he receives. As he bounces between the two different hospitals, he is forced to dig deeper and deeper into Japan's largely corrupted medical society and starts to question even his own initial beliefs, as he asks himself just what being a doctor means. (Source: ANN)

This is not your everyday manga. It strictly deals with cases of intersexuality. I.S. stands for Inter Sexuality. This manga deals with the struggles of intersex people: the pain they go through, the troubles they confront, and ultimately their inability to reproduce or even find a partner who will accept them as they are. The series broken down into individual cases; each deals with different people, though some cases are much longer and more dramatic than others.

Born during the sunrise—an auspicious beginning—the Azumas' newborn son is named Hikaru, which means "light." But during one play date, his mother notices that her son is slightly different from the other children. In this alternately heartwarming and bittersweet tale, a young mother tries to cope with both the overwhelming discovery of her child's autism and the trials of raising him while keeping her family together. This is a story that resonates not only for those whose families have been affected by autism, but also for all past, present, and future parents. (Source: Yen Press) Included one-shots: Volume 15: Thank You Sensei!, Haru no Manazashi

Far in the future, humankind has evacuated the Earth in order to preserve it. Humans now reside in a gigantic structure that forms a ring around the Earth, thirty-five kilometers up in the sky. The society of the ring is highly stratified: the higher the floor, the greater the status. Mitsu, the lowly son of a window washer, has just graduated junior high. When his father disappears and is assumed dead, Mitsu must take on his father's occupation. As he struggles with the transition to working life, Mitsu's job treats him to an outsider's view into the various living-room dioramas of the Saturn Apartments. (Source: VIZ Media)

Welcome to the world of Animal Country. In this world, there exists thousands of animals except for 1; man. That is, until a strange baby was found by the young raccoon Monoko. Now, she has made it her duty to be the child's mother in this world where the strong eat and the weak are eaten! Included one-shot: Volume 6: Konjiki no Gash Bell!! Gaiden: Tomo

The story takes place 2300 years ago in China. The town of Ryo has requested the help of a clan called Bokk to aide them as their town is facing attack. The Bokk clan's representative, Kakuri, responds to their call for help and attempts to save Ryo from an almost inevitable defeat, from not only outer forces, but also from those who doubt him within. Is he up to the challenge?

Taira Capeta was a 4th grader boy. He had lost his mother when he had been very little. Although he pretended to be tough in front of his father, actually he felt lonely. One day, his father brought junk parts home from his workplace and made a racing cart. Soon, they went to a circuit to drive the cart. However, Capeta found that its frame was bent and it could hardly run straight. But, with his technique he managed the cart. Furthermore, he followed soon after the fast cart and he could nearly leave it behind. The driver in the cart was Minamoto Naomoi, the champion of the East Japan Junior Cart. Looking at their chase, Naomi’s mother, Minamoto Nanako, advised Capeta to take part in the official race. (Source: AnimeNfo)

The Animal Liberation Alliance, an eco-terrorist organization, rescues a pregnant chimpanzee from an animal testing lab—only for it to give birth to a half-human, half-chimpanzee "humanzee" named Charlie! Fifteen years later, Charlie's human foster parents are finally ready to send him to a normal high school, where he makes his first friend: a human girl named Lucy. In the meantime, however, the ALA's stance has become ever more extreme, and now they're here to drag Charlie into their terrorist plot... (Source: Kodansha USA)

In the year 1863, a time fraught with violent social upheaval, samurai of all walks of life flock to Kyoto in the hope of joining the Mibu-Roshi—a band of warriors united around their undying loyalty to the Shogunate system. In time, this group would become one of the greatest (and most famous) movements in Japanese history... the Shinsengumi! Into this fierce milieu steps Seizaburou Kamiya, a young would-be warrior who, though lacking in combat experience, possesses a fiery enthusiasm to both aid the Mibu-Roshi in their mission and to avenge his wrongfully murdered family. One of the Mibu-Roshi's most gifted (and immature) swordsmen, the legendary Souji Okita, agrees to take Seizaburou under his wing. What no one suspects, least of all Souji, is that Seizaburou is actually a girl named Sei Tominaga in disguise! (Source: Viz Media) Included one-shot: Volume 45: Ooedo Shinsengumi!

Hell is a bureaucracy and business is running smoother than ever thanks to the demonic efficiency of Hoozuki, the chief deputy to Lord Enma, King of Hell. Whether it be offering counselling to Momotarou of Japanese folklore fame or receiving diplomatic missions from the Judeo-Christian hell; the man who runs the show from behind the Lord Enma's imposing shadows is ready to beat down to a bloody pulp any challenges coming his way, metaphorically of course... As the poster boy for micromanagement and armed with negotiation skills worthy of Wall Street, days spent troubleshooting hell with the sadistic and level-headed Hoozuki are never dull. Full of familiar faces from popular Japanese legends and East Asian mythology working middle management positions, this referential and anachronistic dark comedy set in the underworld brings new meanings to the phrase employer liability. Just how hard can it be to manage employees from hell anyway? [Written by MAL Rewrite]

Azumi focuses upon the life of the female assassin Azumi. The manga begins an indeterminate number of years after the Battle of Sekigahara, but as the Azumi begins her assassination missions, the manga introduces the characters into mainstream history. Many of the early assassination missions that Azumi undertakes are the assassinations of the prominent supporters and generals of the Toyotomi Clan, against whom the Toyotomi Clan expected to again go to war. (Source: Wikipedia)

Left in Pony's Home orphanage as a baby, Candace "Candy" White grew up to be a boisterous and energetic girl. But when her best friend of six years, Annie, is finally adopted by a wealthy family, Candy is upset to lose her. Crying on the hill near her orphanage, the young girl meets a princely boy clothed in Scottish attire, who plays his bagpipe to comfort her. This encounter causes her to dub him the "Prince of the Hill," as he did not reveal his name to her. Six years later at the age of 12, Candy is taken in to be a companion for Eliza and Neil Leagen—siblings who treat her terribly. At her new home, she meets Anthony Brown, a boy who seemingly resembles that prince-like character she once met! Possibly reunited, Candy now finds herself at the start of a journey she will never forget. [Written by MAL Rewrite]

Hikari's your typical freshmen in high school who's been recently daydreaming about Mari's, her shy best friend, love story. She decides to ship Mari with Ootani-kun, their classmate, after finding out about his crush on Mari when his friend, Asagiri-kun, tried getting the two to talk. The main character is Mari, the leading man is Ootani, and Hikari is the typical best friend in the story. Not bad... right? A youthful story between four kids going through unrequited love. (Source: Kodansha, translated)

Tadayasu Sawaki has a gift: he can see all kinds of microbes, from the ones that ferment sake to everyday bathroom mold. Not only that, but they're not scientifically accurate but instead cute chibi creatures. When he enters an agricultural university and a professor finds out about his gift, he begins to meet new people that help him discover more about his abilities and himself.

Shirou Kakei, a straitlaced lawyer, cooks gourmet dinners for himself and his longtime gay lover, Kenji Yabuki, a carefree, hippie-ish hairdresser. The story is told through the lens of dinner preparation. (Source: Entropy)

Mizuho Suga believes that people can be categorized into particular groups, behaving true to form. Since she can predict how others will act, she feels that she understands them. While attending the funeral of a former classmate, Haruka Origichi, she finds it unfortunate that someone died at such a young age. But her impression of Origichi had been that she kept to herself and was unnoticeable, and as such, her life must also have been unremarkable. After the funeral, Suga is approached by Origuchi's mother, who mistakenly assumes that the two girls were best friends. The elder Origuchi wants to know about an ex-boyfriend that her daughter stubbornly tried to keep secret only years ago; apparently, Origuchi aborted their child before she became ill. Suga agrees to investigate this mystery, gradually gaining the assistance of former upperclassman Takashi Yanai, class celebrity Madoka Setouchi, faithful tag-along Remi Nishida, and enigmatic playboy Hikaru Narumi. Although Suga was not close with Origuchi when she was alive, she is strangely determined to know the other girl better after her death. She starts to piece together the events that happened in their second year of high school. As Suga seeks the truth from those suspected to be involved with Origuchi, she must learn how to open up to others and be more honest herself. [Written by MAL Rewrite]

Meet Haru Tennouji, a charismatic communicator beloved by all, regardless of age or gender. He may come across as easygoing, but beneath that façade lies an unwavering ambition for success. When offered a prestigious position at the nation's largest IT company, "Dragon Bank," he does the unexpected—turning it down in favor of embarking on an entrepreneurial journey alongside his friend, Manabu Taira. Their audacious objective: to amass a staggering 1 trillion dollars. Now, let's introduce Manabu, a brilliant engineer armed with remarkable IT acumen. Personality-wise, he's the antithesis of Haru—introverted, and a tad awkward in social interactions. Having faced rejection from "Dragon Bank" due to his communication challenges, he joins forces with Haru, sharing in the colossal ambition of earning that elusive 1 trillion dollars. (Source: MAL News)

Kobayashi just can't focus—not on studying, not on work—and the adults in his life think he's in danger of becoming a worthless dropout. Then, one day, a strange new presence arrives in his class: an energetic and naïve kid named Uno. Kobayashi saves Uno from getting scammed, and that close encounter launches a new friendship. Uno's definitely a space cadet, but Kobayashi can't help admiring the way he floats through life, and before he knows it, he might start feeling his feet lift off the ground, too... (Source: Kodansha USA)

Heat is a crime story featuring a young man named Tatsumi Karasawa who suddenly rises in the criminal world of Shinjuku, Tokyo, and becomes the leader of a group of amateurs who show no reluctance to face police and gangs alike. His successes in the Tokyo underground make a chief and a yakuza boss plot a conspiracy to eliminate him.

Kinnikuman (a.k.a. Kinniku Suguru) is a cowardly, clumsy, moronic, gyuudon-devouring excuse for a superhero (or Choujin)... who just happens to be the prince of an alien planet. But despite his pathetic appearance, he is very honorable and can become quite powerful when he needs to be. With his sidekick Meat-kun and fellow Choujin's Terryman and Ramenman there to help him, Suguru quests to become the greatest Choujin on the planet. Whether with a combination of tremendous heart and stamina (The Burning Inner Strength) or the "Power of Friendship," Kinnikuman frequently defeats villians 10 times more powerful than him and often causes his enemies to have a change of heart and join him. Though he seems destined to be an idiot forever, slowly but surely Kinnikuman becomes worthy of the title "Hero." Note: Between volumes 36 and 37 publication there's 22 years gap. From volume 38 onwards starts restarted in 2011 version.

1. Hoshi no Koibito (The Lover of Stars) 2. Violight 3. Kusaka Kyoudai (The Kusaka Siblings) 4. Mushi to Uta

The year is 2019, and the Japanese government has recently increased their involvement in censorship of the mass media. The upcoming Tokyo Olympics accelerates their efforts. Depictions deemed obscene by the Japanese government become increasingly difficult to publish, even in manga. Under these circumstances, manga author Hibino Mikio just got an opportunity to publish his horror manga: "Dark Walker." His manga centers around a disease that turns normal people into cannibals during the night. Watch as Mikio finds himself in a manga industry shaken by a war on the freedom of expression. (Source: MangaHelpers)

During the Meiji period, this story centers around an unsuccessful science fiction author who masquerades as the dead son of an industrial magnate. With his new family's riches, he creates a fantastical island to satisfy his desires. In his manga adaptation of The Strange Tale of Panorama Island (panorama-tou kidan), Maruo strays from his usual style of explicit gore while maintaining his trademark: elaborate, elegant art. Sprawling, overwhelming landscapes, a diverse range of uniquely designed characters, and even scenes distorted grotesquely for effect are captured with ease by the talented and experienced mangaka. (Source: MU)

Sachi and her boyfriend Takara are your average high school couple. They go to school together, hang out, and even engage in the more intimate side of dating. However, as time passes, Sachi starts to get the feeling that something isn't right and decides to buy a pregnancy test. Later, in the bathroom of a family restaurant far from her home, she sees the two red lines that will change both her and Takara's life forever... (Source: Seven Seas Entertainment)